UEFA Champions League Prediction: Benfica – Bayer Leverkusen (05-11-2025)

Benfica will host Bayer Leverkusen at Estádio da Luz on Wednesday night, with both teams looking to record their first Champions League win of the season.

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Benfica have cleared the 2.5 goal line in 15 of their last 20 home matches and in each of their previous three fixtures. The Lisbon side average 1.7 goals per game from 13.8 attempts and 5.1 shots on target while allowing about one goal per match, which points to open football at both ends. Vangelis Pavlidis leads the team’s scoring chart on eight goals this season.

Leverkusen also bring a strong attacking profile. They have seen the over 2.5 total hit in seven straight away games and in 14 of their last 20 on the road. The German side average 1.9 goals and 13.3 shots per game, but their defence has been shaky recently, conceding 16 goals in their last five matches.

With both clubs capable of scoring freely yet showing defensive flaws, another high-scoring clash appears the most likely scenario.